Publications

View Dr. Kodadek's publications in PubMed and BioRxiv.

2024

Kodadek, T. (2024) “Catalytic protein inhibitors” Angew. Chem.Int. Ed.2024,e202316726doi.org/10.1002/anie.202316726.

Abboud, S. and Kodadek, T. (2024) “2-Pyrione formation: an efficient method for the solid-phase synthesis of homodimers” Chem. Eur. J. 30, e2023029.

2023

Gui, W. and Kodadek, T. (2023) “Protein degraders: progress, limitations and future directions”” Drug Disc. Online. https://www.drugdiscoveryonline.com/doc/protein-degraders-progress-limitations-future-directions-0001.

Gui, W. and Kodadek, T. (2023) “Reversible assembly of proteolysis targeting chimeras” ACS Chem. Biol., 18, 1582-1593.https://pubs.acs.org/doi/10.1021/acschembio.3c00199

Gui, W. and Kodadek, T. (2023) “Facile synthesis of homodimeric protein ligands” ChemBioChem, 24, e202300392.https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cbic.202300392

2022

Kodadek, T. and Satz, A. (2022) “A history of selection-based high throughput screening technologies for hit identification” Topics In Medicinal Chemistry: DNA-Encoded Libraries”, Springer Press.https://link.springer.com/chapter/10.1007/7355_2022_145

Applications and Limitations of Oxime-Linked “Split PROTACs”.Gui W, Kodadek TJ.Chembiochem. 2022 Jul 8. doi: 10.1002/cbic.202200275. Online ahead of print.PMID: 35802347

Synthesis and Screening of a DNA-Encoded Library of Non-Peptidic Macrocycles.Koesema E, Roy A, Paciaroni NG, Coito C, Tokmina-Roszyk M, Kodadek T.Angew Chem Int Ed Engl. 2022 Apr 5;61(18):e202116999. doi: 10.1002/anie.202116999. Epub 2022 Mar 2.PMID: 35192245

2021

High-Throughput Quality Control Assay for the Solid-Phase Synthesis of DNA-Encoded Libraries of Macrocycles*. Roy A, Koesema E, Kodadek T.Angew Chem Int Ed Engl. 2021 May 17;60(21):11983-11990. doi: 10.1002/anie.202100230. Epub 2021 Apr 13.PMID: 33682283 Free PMC article.

2020

Dickson P., Simanski S., Ngundu J. M., Kodadek T. (2020). Mechanistic Studies of the Multiple Myeloma and Melanoma Cell-Selective Toxicity of the Rpn13-Binding Peptoid KDT-11. Cell chemical biology. S2451-9456(20)30305-6. Advance online publication.

Dickson P., Abegg D., Vinogradova E., Takaya J., An H., Simanski S., Cravatt B.F., Adibekian A., Kodadek T. (2020). Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190. Cell chemical biology. S2451-9456(20)30304-4. Advance online publication.

McEnaney, P., Balzarini, M., Park, H., Kodadek, T., (2020). Structural characterization of a peptoid-inspired conformationally constrained oligomer (PICCO) bound to streptavidin. Chem commun (Camb). 56(72), 10560–10563.

Paciaroni N.G., Ndungu J.M., Kodadek T. (2020) Solid-Phase Synthesis of DNA-Encoded Libraries Via An “Aldehyde Explosion” Strategy. Chem Commun (Camb). 56(34):4656-4659.

Roy A., & Kodadek T. (2020) DELs Inside Cells. Trends in pharmacological sciences. 41(4), 225-227.

2019

Kodadek T., Paciaroni N.G., Balzarini M., Dickson P. (2019) Beyond protein binding: recent advances in screening DNA-encoded libraries. Chem Commun. 55(89):13330-13341.

Doran TM., Dickson P., Ndungu J.M., Ge P., Suponitsky-Kroyter I., An H., Kodadek T. (2019) Synthesis and screening of bead-displayed combinatorial libraries. Methods Enzymol. 622:91-127.

Dickson P., Kodadek T. (2019) Chemical composition of DNA-encoded libraries, past present and future. Org Biomol Chem. 15:17(19):4676-4688

Dickson P., Kodadek T. (2019) Sweetening the Therapeutic Pot for Type 2 Diabetes with Long Noncoding RNAs. Cell Chem Biol. 26(3):311-313.

2018

Feng N., Simanski S., Islam K., Hynan L.S., Kodadek T., German D.C. (2018) Antibody Biomarker for de novo Parkinson Disease: Attempted Validation. NPJ Parkinsons Dis. 4:28.

Balzarini M., Kodadek T. (2018) A “Smart Lock” for Preventing Hepatitis B entry into Cells. Cell Chem Biol. 25(7):804-806.

Shu K., Kodadek T. (2018) Solid-Phase Synthesis of B-Hydroxy Ketones Via DNA-Compatible Organocatalytic aldol reactions. ACS Combi Sci. 20(5):277-281.

Erharuyi O., Simanski S. McEnaney P.J., Kodadek T. (2018) Screening one bead one compound libraries against serum using a flow cytometer: Determination of the minimum antibody concentration required for ligand discovery. Bioorg Med Chem Lett. 28(16):2773-2778.

Tran-Hoang N., Kodadek T. (2018) Solid-Phase Synthesis of B-amino Ketones Via DNA-Compatible Organocatalytic Mannich Reactions. ACS Comb Sci. 20(2):55-60.

Pels K., Dickson P., An H., Kodadek T. (2018) DNA-compatible solid-phase combinatorial synthesis of B-cyanoacrylamides and related electrophiles. ACS Comb Sci. 20(2):61-69.

2017

Kodadek T. (2017) Another One (of the “Undruggable” Targets) Bites the Dust: Discovery of a Potent and Selective Inhibitor of the Histone Acetyl Transferase p300/CBP. Biochemistry. 57(6):899-900.

Koesema E., Kodadek T. (2017) Global analysis of gene expression mediated by OX1 orexin receptor signaling in a hypothalamic cell line. Plos One. 12(11):e0188082.

Wu Hao, An H, Mo S, Kodadek T. (2017) Asymmetric Synthesis of Vinylogous β-Amino Acids and Their Incorporation Into Mixed Backbone Oligomers. Org Biomol Chem. 15(15):3255-3264.

Trader DJ, Simanski S, Dickson P, Kodadek T. (2017) Establishment of a suite of assays that support the discovery of proteasome stimulators. Biochim Biophys Acta. 1861(4):892-899.

Mendes KR, Malone ML, Ndungu JM, Suponitsky-Kroyter I, Cavett VJ, McEnaney PJ, MacConnell AB, Doran TM, Ronacher K, Stanley K, Utset O, Walzl G, Paegel BM, Kodadek T. (2017) High-throughput Identification of DNA-Encoded IgG Ligands that Distinguish Active and Latent Mycobacterium tuberculosis Infections. ACS Chem Biol. 12(1):234-243.

2016

Wu H, Mousseau G, Mediouni S, Valente ST, Kodadek T. (2016) Cell-Permeable Peptides Containing Cycloalanine Residues. Angew Chem Int Ed Engl. 55(41):12637-42.

Wu SY, Nin DS, Lee AY, Simanski S, Kodadek T, Chiang CM. (2016) BRD4 Phosphorylation Regulates HPV E2-Mediated Viral Transcription, Origin Replication, and Cellular MMP-9 Expression. Cell Rep. 16(6):1733-48.

Doran TM, Morimoto J, Simanski S, Koesema EJ, Clark LF, Pels K, Stoops SL, Pugliese A, Skyler JS, Kodadek T. (2016) Discovery of Phosphorylated Peripherin as a Major Humoral Autoantigen in Type 1 Diabetes Mellitus. Cell Chem. Biol. 23(5):618-28.

Gearhart TL, Montelaro RC, Schurdak ME, Pilcher CD, Rinaldo CR, Kodadek T, Park Y, Islam K, Yurko R, Marques ET Jr, Burke DS. (2016) Selection of a potential diagnostic biomarker for HIV infection from a random library of non-biological synthetic peptoid oligomers. J Immunol Methods.435:85-9.

Sarma BK, Liu X, Kodadek T. (2016) Identification of selective covalent inhibitors of platelet activating factor acetylhydrolase 1B2 from the screening of an oxadiazolone-capped peptoid-azapeptoid hybrid library. Bioorg. Med Chem 24(17):3953-63.

Doran TM, Sarkar M, Kodadek T. (2016) Chemical Tools to Monitor and Manipulate Adaptive Immune Responses. J Am Chem Soc. 138(19):6076-94.

Clark LF, Kodadek T. (2016) The Immune System and Neuroinflammation as Potential Sources of Blood-Based Biomarkers for Alzheimer’s Disease, Parkinson’s Disease, and Huntington’s Disease. ACS Chem Neurosci.7(5):520-7.

Kodadek T, McEnaney PJ. (2016) Towards vast libraries of scaffold-diverse, conformationally constrained oligomers. Chem Commun (Camb.)52(36):6038-59.

Sarkar M, Liu Y, Qi J, Peng H, Morimoto J, Rader C, Chiorazzi N, Kodadek T. (2016) Targeting Stereotyped B Cell Receptors from Chronic Lymphocytic Leukemia Patients with Synthetic Antigen Surrogates. J Biol Chem.291(14):7558-70.

2015

Clark LF, Kodadek T. (2015) And then there were two. Elife. Dec 30;4.

Doran TM, Morimoto J, Simanski S, McEnaney PJ, Kodadek T. (2015) Reliable diagnosis of murine type 1 diabetes using a panel of autoantigens and “antigen surrogates” mounted onto a liquid array. Mol Biosyst. 11(11):3156-63.

Mendes K, Ndungu JM, Clark LF, Kodadek T. (2015) Optimization of the Magnetic Recovery of Hits from One-Bead-One-Compound Library Screens. ACS Comb Sci. 17(9):506-17.

Li X, Patterson JT, Sarkar M, Pedzisa L, Kodadek T, Roush WR, Rader C. (2015) Site-Specific Dual Antibody Conjugation via Engineered Cysteine and Selenocysteine Residues. Bioconjug Chem. 26(11):2243-8.

Doran TM, Gao Y, Simanski S, McEnaney P, Kodadek T. (2015) High affinity binding of conformationally constrained synthetic oligomers to an antigen-specific antibody: Discovery of a diagnostically useful synthetic ligand for murine Type 1 diabetes autoantibodies. Bioorg Med Chem Lett.25(21):4910-7.

Morimoto J, Kodadek T. (2015) Synthesis of a large library of macrocyclic peptides containing multiple and diverse N-alkylated residues. Mol Biosyst.11(10):2770-9.

Trader DJ, Simanski S, Kodadek T. (2015) A reversible and highly selective inhibitor of the proteasomal ubiquitin receptor Rpn13 is toxic to multiple myeloma cells. J. Amer. Chem. Soc. 137(19):6312-9.

Pels K, Kodadek T. (2015) Solid-phase synthesis of diverse peptide tertiary amides by reductive amination. ACS Comb Sci. 17(3):152-5.

Gao, Y. and Kodadek, T. (2015) Direct comparison of linear and macrocyclic compounds as a source of protein ligands. ACS Comb. Sci. 17(3):190-5.

Cravatt BF, Kodadek T. (2015) Editorial overview: Omics: Methods to monitor and manipulate biological systems: recent advances in “omics.” Curr Opin Chem Biol.

Doran, T.M., Simanski, S. and Kodadek, T. (2015) Discovery of native autoantigens via antigen surrogate technology: Application to type 1 diabetes. ACS Chem. Biol. 10(2):401-12.

Sarkar, M., Liu, Y., Morimoto, J., Peng, H., Aquino, C., Rader, C., Chiorazzi, N. and Kodadek, T. (2015) Recognition of antigen-specific B cell receptors from chronic lymphocytic leukemia patients by synthetic antigen surrogates. Chem & Biol. 21, 21(12):1670-9.

Gao, Y., Amar, S., Pahwa, S., Fields, G. and Kodadek, T. (2015) Rapid lead discovery through iterative screening of one bead one compound libraries. ACS Comb. Sci. 17(1):49-59.

2014

Sarma BK, Liu X, Wu H, Gao Y, Kodadek T. (2014) Solid phase synthesis of 1,3,4-oxadiazin-5 (6R)-one and 1,3,4-oxadiazol-2-one scaffolds from acyl hydrazides. Org Biomol Chem. 12, 59-63.

Morimoto J, Sarkar M, Kenrick S, Kodadek T. (2014) Dextran as a Generally Applicable Multivalent Scaffold for Improving Immunoglobulin-Binding Affinities of Peptide and Peptidomimetic Ligands. Bioconjug Chem. 25, 1479-1491.

Kodadek T. (2014) Chemical tools to monitor and manipulate the adaptive immune system. Chem Biol. 21(9):1066-74.

Suwal S, Kodadek T. (2014) Solid-phase synthesis of peptoid-like oligomers containing diverse diketopiperazine units. Org Biomol Chem. 12(31):5831-4.

Doran TM, Gao Y, Mendes K, Dean S, Simanski S, Kodadek T. (2014) Utility of redundant combinatorial libraries in distinguishing high and low quality screening hits. ACS Comb Sci. 16(6):259-70.

Vanderstichele H, Kodadek T. (2014) Roadblocks for integration of novel biomarker concepts into clinical routine: the peptoid approach.  Alzheimers Res Ther. 6(2):23.

Gao Y, Kodadek T. (2014) Split-and-pool synthesis and characterization of peptide tertiary amide library. J Vis Exp. (88):e51299.

Quan J, Lakhanpal A, Reddy MM, Zaman S, Li QZ, German DC, Olsen NJ, Kodadek T, Karp DR. (2014) Discovery of biomarkers for systemic lupus erythematosus using a library of synthetic autoantigen surrogates. J Immunol Methods. 402(1-2):23-34.

Doran TM, Kodadek T. (2014) A liquid array platform for the multiplexed analysis of synthetic molecule-protein interactions. ACS Chem Biol. 9(2):339-46.

2013

Kodadek T. (2013) A jack of all trades to combat drug-resistant Gram-negative bacteria. Chem Biol. 20(10):1202-3.

Rzuczek SG, Gao Y, Tang ZZ, Thornton CA, Kodadek T, Disney MD. (2013) Features of modularly assembled compounds that impart bioactivity against an RNA target.  ACS Chem Biol. 8(10):2312-21

Clark, L.F. and Kodadek, T. (2013) Advances in blood-based protein biomarkers for Alzheimer’s disease. Alzheimer’s Research & Therapy 5, 18-25.

Sarkar, M., Pascal, B.D., Steckler, C., Micalizio, G.C., Kodadek, T. and Chalmers, M.J. (2013) Decoding split and pool combinatorial libraries with electron transfer dissociation tandem mass spectrometry. J. Amer. Soc. Mass Spec. 24, 1026-1036.

Gao, Y. and Kodadek, T. (2013) Synthesis and Screening of Stereochemically Diverse Combinatorial Libraries of Conformationally Restrained Peptide Tertiary Amides. Chem. & Biol. 20, 360-369.

Raveendra, B., Hao, W., Baccala, R., Reddy, M.M., Schilke, J., Bennett, J.L., Theofilopoulos, A.N. and Kodadek, T. (2013) Discovery of peptoid ligands for anti-Aquaporin 4 antibodies. Chem. & Biol. 20, 351-359

Suwal, S. and Kodadek, T. (2013) Synthesis of Libraries of Peptidomimetic Compounds Containing A 2-Oxopiperazine Unit In The Main Chain. Org. Biomol. Chem. 11, 2088 – 2092.

2012

Sarma, B.K. and Kodadek, T. (2012) Sub-Monomer Synthesis of A Hybrid Peptoid-Azapeptoid Library. ACS Comb. Sci. 14, 558-564.

Liu, X. Dix, M., Speers, A.E., Bachovchin, D.A., Zuhl, A.M., Cravatt, B.F. and Kodadek, T. (2012) Rapid Development of a Potent Photo-Triggered Inhibitor of the Serine Hydrolase RBBP9. ChemBioChem. 13, 2082-2093.

Simpson, L. and Kodadek, T. (2012) A cleavable scaffold strategy for the synthesis of one-bead one-compound cyclic peptoid libraries that can be sequenced by tandem mass spectrometry. Tet.Lett. 53, 2341-2344.

Udugamasooriya DG, Kodadek T. (2012) On-Bead Two-Color (OBTC) Cell Screen for Direct Identification of Highly Selective Cell Surface Receptor Ligands. Curr Protoc Chem Biol. 4:35-48.

Aditya, A. and Kodadek, T. (2012) Incorporation of heterocycles into the backbone of peptoids to generate diverse peptoid-inspired one bead one compound libraries. ACS Comb. Sci. 14, 164-169.

2011

Aquino, C., Sarkar, M., Chalmers, M.J., Mendes, K., Kodadek, T. and Micalizio, G. (2011) A Biomimetic polyketide-inspired approach to small molecule ligand discovery. Nature Chemistry 4, 99-104.

Chen X, Wu J, Luo Y, Liang X, Supnet C, Kim MW, Lotz GP, Yang G, Muchowski PJ, Kodadek T, Bezprozvanny I. (2014) Expanded polyglutamine-binding peptoid as a novel therapeutic agent for treatment of Huntington’s disease. Chem Biol. 18(9):1113-25.

Mendes, K. and Kodadek, T. (2011) PDZ dimerization brings proteins together. Chem. & Biol. 18, 1071-1072.

Sarma, B.K., Yousufuddin, M. and Kodadek, T. (2011) Acyl hydrazides as peptoid sub-monomers. Chem. Comm 47, 10590-10592.

Cai, D., Lee, A.Y., Chiang, C.-M. and Kodadek, T. (2011) Peptoid ligands that bind selectively to phosphoproteins. Bioorg. Med. Chem. Lett. 21, 4960-4964.

Kodadek, T. (2011) The rise, fall and reinvention of combinatorial chemistry. Chem. Comm. 47, 9757-9763.

Reddy, M.M., Wilson, R., Wilson, J., Connell, S., Gocke, A., Hynan, L., German, D. and Kodadek, T. (2011) Identification of candidate IgG biomarkers for Alzheimer’s disease via combinatorial library screening. Cell144, 132-142.

2010

Kodadek T, Cai D, (2010) Chemistry and biology of orexin signaling. Mol Biosyst. 6(8):1366-75

Kodadek T. (2010) Synthetic receptors with antibody-like binding affinities. Curr Opin Chem Biol. 14(6):713-20.

Kodadek T. (2010) Development of antibody surrogates for the treatment of cancers and autoimmune disease. Curr Opin Chem Biol. 14(6):721-7.

Astle, JM, Simpson LS, Huang Y. Reddy, MM, Wilson, R, Connell S, Wilson J, Kodadek T., (2010)  Seamless bead to microarray screening:  rapid identification of teh highest affinity protein ligands from large combinatorial librairies.  Chem Bio 17(1):38-45.

Lee, J., Reddy, M.M. and Kodadek, T. (2010)  Discovery of an orexin receptor positive potentiator.  Chem Sci. 1, 48-54.

Lee, J., Udugamasooriya, D.G., Lim, H.-S. and Kodadek, T. (2010) Potent and selective photo-inactivation of proteins with peptoid-ruthenium conjugates. Nature Chem. Biol. 6, 258-260.

Kodadek, T. (2010) Rethinking screening. Nature Chem. Biol. 6, 162-165.

2009

Gocke, A. R., Udugamasooriya, D.G., Archer, C.T., Lee, J. and Kodadek, T. (2009) Isolation of antagonists of antigen-specific autoimmune T cell proliferation. Chem. & Biol. 16, 1133-1139.

Chan, Y.-C., Wu, S.-Y., Lim, H.-S., Chiang, C.-M. and Kodadek, T. (2009) Non-proteolytic regulation of p53-mediated transcription through destabilization of the activator-promoter complex by the proteasomal ATPases. J. Biol. Chem. 284, In press.

Qi, X., Astle, J. and Kodadek, T. (2009) Rapid identification of orexin receptor ligands using cell-based screening accelerated with magnetic beads. Molecular BioSystems 5, In press.

Liu, B. and Kodadek, T. (2009) Investigating the Cellular Permeability of DNA-binding Pyrrole-Imidazole Polyamides. J. Med. Chem. 52, 4604-4612.

Lim, H.-S., Reddy, M.M., Xiao, X., Wilson, J., Wilson, R., Connell, S. and Kodadek, T. (2009) Rapid identification of improved protein ligands using peptoid microarrays. Bioorganic Med. Chem. Lett. 19, 3866-3869.

Zuckermann, R.N. and Kodadek, T. (2009) Peptoids as potential therapeutics. Curr. Opin. Mol. Therapeutics. 11, 299-307.

Simpson, L.S., Burdine, L., Dutta, A.K., Feranchak, A.P. and Kodadek, T. (2009) Selective Toxin Sequestrants for the Treatment of Bacterial Infections. J. Amer. Chem. Soc. 131, 5760-5762.

Friedberg, E.C. and Kodadek, T. (2009) Nucleic Acids: Chemical Damage. Volume 3, 467-480 in Wiley Encyclopedia of Chemical Biology. John Wiley & Sons, Inc., Hoboken, N.J.

2008

Archer, C.T., Burdine, L., Liu, B., Ferdous, A., Johnston, S.A. and Kodadek, T. (2008) Physical and functional interaction of mono-ubiquitylated transactivators with the proteasome. J. Biol. Chem. 283, 21789-21798.

Kwon, Y.-U. and Kodadek, T. (2008) Encoded combinatorial libraries for the construction of cyclic peptoid microarrays. Chem. Comm. 5704-5706.

Udugamasooriya, D.G., Dunham, G., Ritchie, C., Brekken, R.A. and Kodadek, T. (2008) The pharmacophore of a peptoid VEGF Receptor antagonist includes both side chain and main chain residues. Bioorg, Med. Chem. Lett. 18, 5892-5894.

Kodadek, T. (2008) Rise of the machines: Bruce Alberts and the biochemistry of multi-protein complexes. Mol. BioSystems. 4, 1043-1045.

Ferdous, A., O’Neal, M., Nalley, K., Sikder, D., Kodadek, T. and Johnston, S.A. (2008) Phosphorylation of the Gal4 DNA-binding domain is essential for activator mono-ubiquitylation and effeficient promoter occupancy. Mol. BioSystems. 4, 1116-1125.

Archer, C.T., Burdine, L., Liu, B., Ferdous, A., Johnston, S.A. and Kodadek, T. (2008) Physical and functional interaction of mono-ubiquitylated transactivators with the proteasome. J. Biol. Chem. 283, 21789-21798.

Astle, J.M., Udugamasooriya, D.G., Smallshaw, J.E. and Kodadek, T. (2008) A VEGFR2 antagonist and other peptoids evade immune recognition. Intl. J. Peptide Res. & Therapeutics. 14, 223-227.

Kodadek, T. (2008) Molecular cloaking devices. Nature. 453, 861-862.

Tan, N.C., Yu, P., Kwon, Y.-U. and Kodadek, T. (2008) High-throughput evaluation of relative cell permeability between peptoids and peptides. Bioorg. Med. Chem. 16, 5853-5861.

Kodadek, T. (2008) Proteomes take the electrophilic bait. Nature Chem. Biol. 4, 387-388.

Udugamasooriya, D.G., Ritchie, C., Brekken, R.A. and Kodadek, T. (2008) A Peptoid Antagonist of VEGF Receptor 2 Recognizes A Hotspot In the Extracellular Domain Distinct From The Hormone-Binding Site. Bioorg. & Med. Chem. 16, 6338-6343.

Hanaoka, K., Lubag, A.J.M., Castillo-Muzquiz, A., Kodadek, T. and Sherry, A.D. (2008) The detection limit of a Gd3+-based T1 agent is substantially reduced when targeted to a protein microdomain. Mag. Res. Imaging. 26, 608-617.

Udugamasooriya, D.G., Dineen, S.P., Brekken, R.A. and Kodadek, T. (2008) A peptoid antibody surrogate that antagonizes VEGF Receptor 2 activity. J. Amer. Chem. Soc. 130, 5744-52.

Archer, C.T., Delahodde, A., Gonzalez, F., Johnston, S.A. and Kodadek, T. (2008) Activation domain-dependent mono-ubiquitylation of Gal4 protein is essential for promoter binding in vivo. J. Biol. Chem. 283, 12614-12623.

Shores, K.S., Udugamasooriya, D.G., Kodadek, T. and Knapp, D.R. (2008) Use of peptide analog diversity library beads for increased depth of proteomic analysis: Application to cerebrospinal fluid. J. Proteome Res. 7, 1922-1931.

Marthandan, N., Klyza, S., Li, S., Kodadek, T. and Garner, H.R. (2008) Construction and evaluation of an automated light directed protein-detecting microarray synthesizer. IEEE Transactions in NanoBioscience. 7, 20-27.

Lim, H.-S., Archer, C.T., Kim, Y.-C., Hutchens, T. and Kodadek, T. (2008) Rapid identification of the pharmacophore in a peptoid inhibitor of the proteasome regulatory particle. Chem. Comm. 1064-1066.

Lee, J., Yu, P., Xiao, X. and Kodadek, T. (2008) A General System for Evaluating the Efficiency of Chromophore-Assisted Light Inactivation (CALI) of Proteins Reveals Ru(II) tris-bipyridyl As An Unusually Efficient Warhead. Molecular BioSystems. 4, 59-65.

2007

Astle, J. Ferguson, JT. German, JB. Harrigan, GG. Kelleher, NL. Kodadek, T. Parks, BA. Roth, MJ. Singletary, KW. Wenger, CD. Mahady, G.B. (2007) Characterization of proteomic and metabolomic responses to dietary factors and supplements. J. of Nutrition. 137, 2787-2793.

Yu, P. and Kodadek, T. (2007) Dynamics of the Hypoxia-Inducible Factor-1-VEGF promoter complex. J. Biol. Chem. 282, 35035 – 35045.

Lim, H.-S., Cai, D. and Kodadek, T. (2007) Chemical cross-linking reveals Sug2/Rpt4 as the molecular target of a peptoid inhibitor of the 19S proteasome regulatory particle. J. Amer. Chem. Soc. 129, 12936-12937.

Sikder, D. and Kodadek, T. (2007) The neurohormone orexin stimulates hypoxia-inducible factor-1 activity. Genes & Devel. 21, 2995-3005

Liu, B., Archer, C.T., Burdine, L., Gillette, T.G. and Kodadek, T. (2007) Label transfer chemistry for the characterization of protein-protein interactions. J. Amer. Chem. Soc. 129, 12348-12349.

Kwon, Y.-U. and Kodadek, T. (2007) Quantitative comparison of the relative cell permeability of cyclic and linear peptides. Chem. & Biol. 14, 671-677.

Lim, H.-Y., Archer, C.T. and Kodadek, T. (2007) Identification of a peptoid inhibitor of the proteasome 19S regulatory particle. J. Amer. Chem. Soc.129, 7750-7751.

Xiao, X., Yu, P., Lim, H.-Y., Sikder, S. and Kodadek, T. (2007) Design and synthesis of a cell permeable transcription factor mimic. J. Comb. Chem. 9, 592-600.

Xiao, X., Yu, P., Lim, H.-S., Sikder, D. and Kodadek, T. (2007) A cell permeable transcription factor mimic. Angew. Chem. Intl. Ed. 46, 2865-2868.

Yu, P. and Kodadek, T. (2007) A convenient, high-throughput strategy for measuring the relative cell permeability of synthetic compounds. Nature Protocols. 2, 23-30.

Kwon, Y.-U. and Kodadek, T. (2007) Quantitative evaluation of the relative cell permeability of peptoids and peptides. J. Amer. Chem. Soc. 129, 1508-1509.

Ferdous, A., Sikder, D., Gillette, T., Nalley, K., Kodadek, T. and Johnston, S.A. (2007) The Role of the Proteasomal ATPases and Activator Mono-Ubiquitylation in Regulating Gal4 Binding to Promoters. Genes & Dev. 21, 112-123.

2006

Liu, B., Burdine, L. and Kodadek, T. (2006) Chemistry of periodate-mediated cross-linking of 3,4-dihydroxyphenlalanine (DOPA)-containing molecules to proteins. J. Amer. Chem. Soc. 128, 15228-15235.

Page, T., Sikder, D. Yang, L. Pluta, L., Wolfinger, R.D., Kodadek, T. and Thomas, R.S. (2006) Genome-wide analysis of human HSF1 signaling reveals a transcriptional program linked to cellular adaptation and survival. Molecular BioSystems. 2, 627-639.

Kodadek, T., Sikder, D. and Nalley, K. (2006) Keeping transcriptional activators under control. Cell. 127, 261-264.

Sikder, D., Johnston, S.A. and Kodadek, T. (2006) Widespread, but non-identical, association of proteasomal 19S and 20S proteins with yeast chromatin. J. Biol. Chem. 281, 27346-27355.

Nalley, K., Johnston, S.A. and Kodadek, T. (2006) Proteolytic turnover of Gal4 is not required for function in vivo. Nature. 442, 1054-1057.

Alluri, P., Liu, B., Yu, P., Xiao, X. and Kodadek, T. (2006) isolation and chearacterization of coactivator-binding peptoids from a combinatorial library. Molecular Biosystems. 2, 568-579.

Sulahian, R., Sikder, D., Johnston, S.A. and Kodadek, T. (2006) The Proteasomal ATPase Complex Is Required For Stressed-Induced Trasncription in Yeast. Nucl. Acids Res. 34, 1351-1357.

Sikder, K. and Kodadek, T. (2006) Optimized protocols for the isolation of specific protein-binding peptides or peptoids from combinatorial libraries displayed on beads. Molecular BioSystems. 2, 25-35.

2005

Archer, C., Burdine, L. and Kodadek, T. (2005) Identification of Gal4 transactivation domain binding proteins in the 26S proteasome by perioddate-triggered cross-linking. Molecular BioSystems. 1, 366-372.

Liu, B., Yu, P., Alluri, P.G. and Kodadek, T. (2005) Simple reporter gene-based assays for hairpin polyamide conjugate permeability and DNA-binding activity in living cells. Molecular BioSystems. 1, 307-317.

Reddy, M.M. and Kodadek, T. (2005) Protein ‘fingerprinting’ in complex mixtures using peptoid microarrays.  Proc. Natl. Acad. Sci. USA 102, 12672-12677.

Liu, B., Alluri, P., Yu, P. and Kodadek, T. (2005) A KIX-binding peptoid functions as a transactivation domain in mammalian cells.  J. Amer. Chem. Soc. 127, 8254-8255.

Yu, P., Liu, B. and Kodadek, T. (2005) A high-throughput assay for assessing the cell permeability of combinatorial libraries. Nature Biotechnol. 23, 746-751.

Li, S., Marthandan, N., Bowerman, D., Garner, H.R. and Kodadek, T. (2005) Photolithographic synthesis of cyclic peptide arrays using a differential deprotection strategy. Chem. Comm. (5): 581-583.

2004

Troitskaya, L. and Kodadek, T. (2004) “Peptides as modulators of enzymes and regulatory proteins” Methods 32, 406-415.

Denison, C. and Kodadek, T. (2004) “Towards a general chemical method for mapping the architecture of multi-protein complexes” J. Proteome Res. 3, 417-425.

Smith, A.H., Vrtis, J.M. and Kodadek, T. (2004) “The Potential of Protein-Detecting Microrrays for Clinical Diagnostics” Clinical Chem 37, 217-238

Gillette, T., Gonzalez, F.G., Delahodde, A., Johnston, S.A. and Kodadek, T. (2004) “Physical and Functional Association of RNA Polymerase II and the Proteasome” Proc. Natl. Acad. Sci. USA 101, 5904-5909.

Burdine, L. and Kodadek, T. (2004) “Protein target identification: The (often) missing link in chemical genetics” Chem. & Biol. 11, 593-597.

Moola, R., Bacchawat –Sikder, K. and Kodadek, T. (2004) “Transformation of low affinity lead compounds into high affinity protein capture agents”Chem. & Biol. 11, 1127-37.

Kodadek, T., Reddy, M.M.,  Olivos, H.J., Bachhawat-Sikder , K. and Alluri, P.G. (2004) “Synthetic molecules as antibody replacements” Acc. Chem. Res. 37, 711-718.

Burdine, L., Gillette, T.G., Lin, H.-J. and Kodadek, T. (2004) “Periodate-triggered cross-linking of DOPA-containing peptide-protein complexes” J. Amer. Chem. Soc. 126, 11442-11443.

Li, S., Bowerman, D.J., Marthandan, N., Garner, H.R. and Kodadek, T. (2004) “Photolithographic synthesis of peptoids” J. Amer. Chem. Soc. 126,  4088-4089.

2003

Bacchawat-Sikder, K. and Kodadek, T. (2003) “Protein detecting microarrays for diagnostics and basic research”Clin. Lab. Intl.  27, 16-18.

Alluri, P.G. Reddy, M.M., Bacchawat-Sikder, K., Olivos, H.J. and Kodadek, T. (2003) “Isolation of protein ligands from large peptoid libraries” J. Amer. Chem. Soc. 125, 13995-14004.

Amini, F., Denison, C., Lin, H.-J., Sun, L. and Kodadek, T. (2003) “Quantitative analysis of protein-protein interactions using oxidative labeling and cross-linking chemistry” Chem. & Biol. 10, 1115-1127.

Liu, B., Han, Y. Ferdous, A., Corey, D.R. and Kodadek, T. (2003) “Transcription Activation by a PNA-Peptide Chimera In A Mammalian Cell Extract” Chem. & Biol. 10, 909-916.

Olivos, H.J., Bacchawat-Sikder, K. and Kodadek, T. (2003) “Quantum dots as a visual aid for screening bead-bound combinatorial libraries” ChemBiochem 4, 1242-1245.

Sikder, K. and Kodadek, T. (2003) “Mixed Element Capture Agents (MECAs): A Simple Strategy For the Construction of Synthetic, High Affinity Protein Capture Ligands” J. Amer. Chem. Soc. 125, 9550-9551.

Naffin, J.L., Han, Y. Sun, T., Reddy, M.M., Olivos, H.J., and Kodadek, T. (2003) “Immobilized peptides as high affinity capture agents for self-associating proteins” Chem. & Biol. 10, 251-259.

2002

Amini, F., Kodadek, T. and Brown, K.C. (2002) “Protein affinity labeling mediated by genetically-encoded peptide tags” Angew. Chem. Intl. Ed. 41, 356-359.

Liu, B., Han, Y., Corey, D.R. and Kodadek, T. (2002) “Towards synthetic transcription activators: recruitment of transcription factors to DNA by a PNA-peptide chimera” J. Amer. Chem. Soc., 124, 1838-1839.

Kodadek, T. (2002) “Protein-detecting microarrays” Trends In Biochem. Sci. 27, 295-300.

De León, L.M.Weiner, A., Zhang, S., Kovacs, Z., Kodadek, T. and Sherry, A.D. (2002) “Magnetic Resonance Imaging Detects a Specific Peptide-Protein Binding Event” J. Amer. Chem. Soc. 124, 3514-3515.

Kodadek, T. (2002) “Inhibition of proteolysis and other post-translational modifications with substrate-targeted inhibitors” Biopolymers – Peptide Science, 66, 134-140.

Sun, L. and Kodadek, T. (2002) “Removal of impurities from transcription factor preparations that alter their DNA-binding properties” Nucl. Acids Res. 30, e88.

Sun, L., Johnston, S.A. and Kodadek, T. (2002) “Physical association of the APIS complex and general transcription factors” Biochem. Biophys. Res. Comm. 296, 991-999.

Ferdous, A., Kodadek, T. and Johnston, S.A. (2002) “A nonproteolytic function of the 19S regulatory subunit of the 26S proteasome is required for efficient activated transcription by human RNA polymerase II” Biochemistry 41, 12798-12805.

Olivos, H.J., Alluri. P.G, Reddy, M.M., Saloney, D. and Kodadek, T. (2002) “Microwave-assisted solid phase synthesis of peptoids” Organic Letters 4, 4057-4059.

Gonzalez, F., Delahoude, A., Kodadek, T. and Johnston, S.A. (2002) A sub-complex of the 19S proteasome regulatory complex is recruited to an activated promoter. Science. 296, 548-550.

2001

Brown, K.C. and Kodadek, T. (2001) “Protein Cross-linking mediated by metal ion complexes” in “Probing proteins by metal ions and their low-molecular-weight complexes”, Vol. 38 of Metal Ions In Biological Systems, pages 351-384, A. Sigel and H. Sigel, eds., M. Dekker, New York.

Kodadek, T. (2001) “Protein microarrays: Prospects and problems” Chem. & Biol. 8, 105-116.

Zhang, Z., Li, T. and Kodadek, T. (2001) “An inhibitor of sequence-specific proteolysis that targets the substrate rather than the enzyme” Chem. & Biol. 8, 391-397.

Jeong, C.-J., Yang^, S.H., Xie, Y., Zhang, L., Johnston, S.A. and Kodadek, T. (2001) “Evidence that Gal11 protein is a target of the Gal4 activation domain in the mediator” Biochemistry, 40, 9421-9427.

Chang, C., Gonzalez, F., Rothermel, B., Sun, L., Johnston, S.A. and Kodadek, T. (2001) “The Gal4 activation domain binds the Sug2 protein, a proteasome component, in vivo and in vitro” J. Biol. Chem. 276, 30956-30963.

Ferdous, A., Gonzalez, F., Sun, L., Kodadek, T. and Johnston, S.A. (2001) The 19S regulatory particle of the proteasome is required for efficient transcription elongation by RNA polymerase II. Mol. Cell. 7, 981-991.

2000 – 1983

Xie, Y., Sun, L. and Kodadek, T. (2000) “Cooperative binding of the Gal4 and TATA-binding proteins to promoters does not contribute substantially to activated transcription” J. Biol. Chem., 275, 40797-40803.

Xie, Y., Denison, C., Yang, S., Fancy, D.A. and Kodadek, T. (2000) “Biochemical characterization of the TATA-binding protein-Gal4 activation domain complex” J. Biol. Chem. 275, 31914-31920.

Zhu, W., Williams, R.S. and Kodadek, T. (2000) “A Cdc6-binding peptide selected using a bacterial two-hybrid-like system is a cell cycle inhibitor” J. Biol. Chem. 275, 32098-32105.

Fancy, D.A., Denison, C., Kim, K., Xie, Y., Holdeman, T., Amini, F. and Kodadek, T. (2000) “Scope, limitations and mechanistic aspects of the photo-induced cross-linking of proteins by water-soluble metal complexes” Chem. & Biol. 7, 697-708.

Han, Y. and Kodadek, T. (2000) “Peptides selected to bind the Gal80 repressor are potent transcriptional activation domains in yeast” J. Biol. Chem.275, 14979-14984.

Brent, R. and Kodadek, T. (2000) “Analysis and Manipulation of Proteins and Protein Complexes: A New Frontier In Chemical Biology and Biotechnology” Curr. Op. Chem. Biol. 4, 13-15.

Kodadek, T. (2000) “Chemistry & Biology: A challenging balancing act” Chem. & Biol. 7, R1-R2.

Zhang, Z., Zhu, W. and Kodadek, T. (2000) “Selection and practical applications of peptide-binding peptides” Nature Biotech. 18, 71-74.

Patikoglou, G.A., Kim, J.L., Sun, L., Yang, S.-H., Kodadek, T. and Burley, S.K. (1999) “TATA element recognition by the TATA box-binding protein has been conserved throughout evolution” Genes & Dev. 13, 3217-3230.

Kim, K., Fancy, D.A. and Kodadek, T. (1999) “Photo-induced protein cross-linking mediated by palladium porphyrins” J. Amer. Chem. Soc. 121,11896-11897.

Fancy, D.A., Kodadek, T. (1999) “Chemistry for the analysis of protein-protein interactions: Rapid and efficient cross-linking triggered by long wavelength light” Proc. Natl. Acad. Sci. USA 96, 6020-6024.  Also see correction, Vol. 97, Issue 3, 1317a-1317a, February 1, 2000.

Zhang, Z., Murphy, A., Hu, J.C. and Kodadek, T. (1999)“Genetic selection of short peptides that support protein oligomerization in vivo” Current Biol. 9, 417-420.

Vashee, S., Willie, J. and Kodadek, T. (1998) “Synergistic activation of transcription by physiologically unrelated transcription factors through cooperative DNA-binding” Biochem Biophys. Res. Comm. 247, 530-535.

Campbell, L., Kodadek, T., and Brown, K.C. (1998) “Metal porphyrins as protein cross-linking reagents” Bioorg Med. Chem. 6, 1301-1307.

Denison, C. and Kodadek, T. (1998) “Small molecule control of gene expression” Chem. & Biol. 5, R129-R145.

Fancy, D.A. and Kodadek, T. (1998) “A critical role for tyrosine residues in His6-Ni-mediated protein cross-linking”  Biochem. Biophys. Res. Comm. 247, 420-426.

Vashee, S., Melcher, K., Ding, W., Johnston, S.A. and Kodadek, T. (1998) “Two novel mechanisms for cooperative binding of transcription factors to promoters in vivo” Curr. Biol. 8, 452-458.

Kodadek, T. (1998) “Mechanistic parallels between DNA replication, recombination and transcription”  Trends In Biochem. Sci. 23, 79-83.

Dresser, M., Ewing, D., Conrad, M., Dominguez, A., Barstead, R., Jiang, H. and Kodadek, T. (1997) “DMC1 functions in a meiotic pathway that is largely independent of the RAD51 pathway” Genetics 147, 533-544.

Fancy, D.A. and Kodadek, T. (1997) “Site-directed, metal-catalyzed oxidative protein crosslinking” Tetrahedron 53, 11953-11960.

Barry, J.F., Campbell, L., Smith, D.W. and Kodadek, T. (1997) “Synthesis and Catalytic Epoxidation Activity of Terpene-Derived D₄-Symmetric Metalloporphyrins” Tetrahedron 53, 7753-7776.

Jiang, H., Salinas, F. and Kodadek, T. (1997) “The gene 32 single-stranded DNA-binding protein does not associate stably with the phage T4 presynaptic filament” Biochem. Biophys. Res. Comm. 231, 600-605.

Campbell, L. and Kodadek, T. (1997) “Chiral porphyrins as catalysts for the asymmetric oxidation of hydrocarbons”  J. Mol. Catal. A: Chemical 113, 293-310.

Jiang, H., Xie, Y.,  Stemke-Hale, K., Houston, P.,  Mortensen, U.H., Rothstein, R. and Kodadek, T. (1996) “Direct Association Between the Yeast Rad51 and Rad54 Recombination Proteins” J. Biol. Chem. 271, 33181-33186.

Fancy, D.A., Melcher, K.;  Johnston, S.A. and Kodadek, T. (1996) “New chemistry for the study of multiprotein complexes: The six histidine tag as a receptor for a protein cross-linking reagent” Chem. & Biol. 3, 551-559.

Sessler, J.L., Lisowski, J., Boudreaux, K., Lynch, V., Barry, J. and Kodadek, T. (1995) “Synthesis and characterization of di-aryl sapphyrins prepared under Lindsey-type conditions” J. Org. Chem. 60, 5975-5978.

Vashee, S. and Kodadek, T. (1995) “The activation domain of GAL4 protein mediates cooperative promoter binding with general transcription factors in vivo”  Proc. Natl. Acad. Sci. USA 92, 10683-10687.

Robbins Wolf, J.,   Hamaker, C.G.,  Djukic, J.-P., Kodadek, T. and Woo, L.K. (1995) “Shape and stereoselective cyclopropanation of alkenes catalyzed by iron porphyrins” J. Amer. Chem. Soc. 117, 9194-9199.

Xu, H.E., Kodadek, T. and Johnston, S.A. (1995) “A single dimer of GAL4 protein can maximally stimulate transcription under physiological conditions” Proc. Natl. Acad. Sci. USA 92, 7677-7680.

Salinas, F. and Kodadek, T. (1995) “Phage T4 homologous strand exchange: A DNA helicase, not the strand transferase, drives polar branch migration” Cell 82, 111-119.

Kodadek, T. (1995) “From carpet bombing to cruise missiles: ‘Second-order’ mechanisms of transcription factor-DNA binding in vivo”  Chem. & Biol. 2, 267-279.

Brown, K.C., Yang, S.-H. and Kodadek, T. (1995) “Highly specific oxidative protein crosslinking mediated by a nickel peptide complex”  Biochemistry  34, 4733-4739.

Salinas, F., Jiang, H. and Kodadek, T. (1995) “Homology dependence of uvsX protein-catalyzed joint molecule formation” J. Biol. Chem.  270, 5181-5186.

Kodadek, T. and Johnston, S.A. (1995) “The dangers of ‘splicing and dicing’: On the use of chimeric transcriptional activators in vitro” Chem. & Biol. 2, 187-194.

Salinas, F. and Kodadek, T. (1994) “Strand exchange through a DNA-protein complex requires a DNA helicase”  Biochem. Biophys. Res. Comm. 205, 1004-1009.

Maine, I.P. and Kodadek, T. (1994) “Efficient unwinding of triplex DNA by a DNA helicase” Biochem. Biophys. Res. Comm. 204, 1119-1124.

Houston, P. and Kodadek, T. (1994) “Spectrophotometric assay for enzyme-mediated unwinding of double-stranded DNA” Proc. Natl. Acad. Sci. USA 91, 5471-5474.

Barry, J. and Kodadek, T. (1994)  “A new route ‘5+1’ route to arenes.  Application to the facile synthesis of D₄-symmetric chiral porphyrins”  Tetrahedron Letters 35, 2465-2468.

Qui, H., Kodadek, T., and Giederoc, D.P. (1994) “Zinc-free and reduced T4 gene 32 protein binds single-stranded DNA weakly and fails to stimulate UvsX-catalyzed homologous pairing” J. Biol. Chem.  269, 2773-278.

Maine, I.P. and Kodadek, T. (1994) “Inhibition of the DNA unwinding and ATP hydrolysis activities of the bacteriophage dda helicase by a sequence specific DNA-protein complex” Biochem. Biophys. Res. Comm. 198, 1070-1077.

Kodadek, T.J. (1994)  “Protein-protein interactions in transcriptional activation” in “Transcription”, Conaway, R. and Conaway, J., Eds., Raven Press, NY.

Kodadek, T. (1993) “How does the GAL4 transcription factor recognize the appropriate DNA binding sites in vivo?” Cell. Mol. Biol. Res. 39, 355-360.

Vashee, S., Xu, H., Johnston, S.A. and Kodadek, T. (1993) “How do Zn2Cys6 proteins distinguish between similar upstream activation sites?  Comparison of the in vivo and in vitro DNA-binding specificities of the GAL4 protein”.  J. Biol. Chem. 268, 24699-24706.

Van Hoy, M., Leuther, K.K., Kodadek, T. and Johnston, S.A. (1993) “The acidic activation domains of the GCN4 and GAL4 proteins are not a-helical, but form b-sheets” Cell 72, 587-594.

Bartley, D.W. and Kodadek, T. (1993)  “Identification of the active catalyst in the rhodium porphyrin-mediated cyclopropanation of alkenes” J. Amer. Chem. Soc. 115, 1656-1660.

Jiang, H., Geideroc, D. and Kodadek, T. (1993)  “The Role of Protein-Protein Interactions in the Assembly of the Presynaptic Filament for T4 Homologous Recombination”  J. Biol. Chem. 268, 7904-7911.

Kodadek, T. (1992) “The molecular basis of sequence-specific DNA-protein interactions” in “Nucleic Acid Targeted Drug Design”, Propst, C. and Perun, T., Eds., Marcel Dekker, NY, ppg. 196-299.

Brown, K.C. and Kodadek, T. (1992)  “A transition state model for the rhodium-catalyzed cyclopropanation of alkenes by diazo esters” J. Amer. Chem. Soc. 114, 8336-8338.

Maxwell, J.L., Brown, K.C., Bartley, D.W. and Kodadek, T.  “Mechanism of the rhodium porphyrin-catalyzed cyclopropanation of alkenes” (1992) Science 256, 1544-1547.

O’Malley, S. and Kodadek, T. (1992) “Asymmetric cyclopropanation of alkenes catalyzed by a rhodium ‘chiral fortress’ porphyrin”  Organometallics 11, 2299-2302.

Maine, I.P., Sun, D., Hurley, L. and Kodadek, T. (1992)  “The antitumor agent CC-1065 inhibits helicase-catalyzed unwinding of duplex DNA” Biochemistry  31, 3968-3975.

Maxwell, J.L., O’Malley, Brown, K.C. and Kodadek. T. (1992) “Shape selective and asymmetric cyclopropanation of alkenes catalyzed by rhodium porphyrins”  Organometallics 11, 645-652.

VanHoy, M., Hansen, A. and Kodadek, T. (1992) “Spectroscopic studies of a transcriptional activation peptide” J. Amer. Chem. Soc. 114,  362-363.

Kodadek, T. (1991) “Inhibition of protein-mediated homologous pairing by a DNA helicase” J. Biol. Chem. 266, 9712-9718.

O’Malley, S. and Kodadek, T. (1991) “Asymmetric cyclopropanation of alkenes catalyzed by a ‘chiral wall’ porphyrin” Tetrahedron Letters 32, 2445-2448.

Hansen, A., VanHoy, M. and Kodadek, T. (1991) “Spectroscopic studies of the DNA binding site for the GAL4 zinc finger protein” Biochem. Biophys. Res. Comm. 175, 492-499.

Maxwell, J. and Kodadek, T. (1991) “Organometallic chemistry of porphyrins: Spectroscopic and chemical characterization of a rhodium porphyrin/ethyldiazo acetate adduct” Organometallics 10, 4-6.

Bartley, D.W. and Kodadek, T. (1990) “Catalysis of Diels-Alder reactions by metalloporphyrins” Tetrahedron Letters 44, 6303-6306.

Kodadek, T. (1990) “Functional interactions between phage T4 and E. coli DNA-binding proteins during the presynapsis phase of homologous recombination” Biochem. Biophys. Res. Commun. 172, 804-10.

Kodadek, T. and Wong, M.-L. (1990) “Homologous pairing in vitro initiated by DNA synthesis” Biochem. Biophys. Res. Comm. 169, 302-309.

Rodriguez, M., Kodadek, T., Torres, M. and Bard, A.J. (1990) “Cleavage of DNA by electrochemically activated Mn(III) and Fe(III) complexes of meso-tetrakis (N-methyl-4-pyridiniumyl) porphine” Bioconjugate Chem. 2, 123-131.

Kodadek, T. (1990) “The role of the bacteriophage gene 32 protein in homologous pairing” J. Biol. Chem. 265, 20966-20969.

Kodadek, T.; Gan, D. C. and Stemke-Hale, K. (1989) “The phage T4 uvs Y recombination protein stabilizes presynaptic filaments” J. Biol. Chem. 264, 16451-16457.

 O’Malley, S. and Kodadek, T. (1989) “Synthesis and characterization of the ‘chiral wall porphyrin’” J. Amer. Chem. Soc. 111, 9116-9117.

  Kodadek, T. and Gamper, H. (1988) “Efficient synthesis of a supercoiled M13 DNA molecule containing a site-specifically placed psoralen adduct and its use as a substrate for DNA replication”  Biochemistry 27, 3210-3215.

  Kodadek, T.; Wong, M. L.; Alberts, B. M. (1988) “Mechanism of strand exchange catalyzed by the bacteriophage uvsX protein” J. Biol. Chem. 263, 9427-9436.

  Kodadek, T.; Alberts, B. M. (1987) “Protein-mediated strand exchange stimulated by a DNA helicase” Nature 326, 312-314.

  Collman, J.P., Kodadek, T. and Brauman, J.I. (1986) “Oxygenation of styrene by cytochrome P-450 model systems: A mechanistic study” J. Amer. Chem. Soc. 108, 2588-2594.

  Collman, J.P., Kodadek, T., Raybuck, S.A., Brauman, J.I. and Papazian, L.M. (1986) “” J. Amer. Chem. Soc. 107, 4343-4344.

  Collman, J.P., Brauman, J.I., Meuneier, B., Hayashi, T., Kodadek, T. and Raybuck, S.A. (1985) “Epoxidation of olefins by cytochrome P-450 model compounds: Kinetics and stereochemistry of oxygen atom transfer and origin of shape selectivity” J. Amer. Chem. Soc. 107, 2000-2005.

  Collman, J.P., Brauman, J.I., Meunier, B., Raybuck, S.A. and Kodadek, T. (1984) “Epoxidation of olefins by cytochrome P-450 model compounds: Mechanism of oxygen atom transfer” Proc. Natl. Acad. Sci. USA 81, 3245-3248.

  Collman, J.P., Kodadek, T., Raybuck, S.A. and Meunier, B. (1983) “Oxygenation of hydrocarbons by cytochrome P-450 model compounds: Modification of reactivity by axial ligands” Proc. Natl. Acad. Sci. USA 80, 7039-7041.